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Besonders bemerkenswert: Eine italienische Fallserie (2025) mit Exenatid zeigte, dass symptomatische Verbesserungen sogar ohne signifikanten Gewichtsverlust eintraten ein starker Hinweis auf extra-metabolische Wirkmechanismen

173 Arginine in cancer Citrulline and aspartate can be converted to arginine in normal cells by arginine-succinate synthetase 1 (ASS1) and arginine-succinate lyase (ASL) in the urea cycle

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Semaglutide operates by mimicking the actions of the natural hormone GLP-1

In published research it has been investigated for its effects on tissue repair, angiogenesis, gastrointestinal mucosal protection and anti-inflammatory signalling in animal and cell-culture models